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Semax

Semax

Regular price £31.00 GBP
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Synthetic ACTH(4-10) analogue developed for neurological research.

Overview

Semax is a synthetic heptapeptide analogue of ACTH(4-10), developed at a Moscow research institute in the 1980s for stroke and cognitive impairment research. The hormonal activity of the parent fragment is engineered out and a Pro-Gly-Pro tail added to resist degradation.

Research applications

  • BDNF upregulation
  • Memory consolidation in research models
  • Neuroprotection following ischaemic events
  • Dopaminergic and serotonergic modulation
  • Neuronal growth and synaptic plasticity

Mechanism of action

Acts on melanocortin receptors and markedly upregulates brain-derived neurotrophic factor, the protein governing neuron growth, maintenance and synaptic plasticity. It also modulates the enkephalin system and influences dopamine, serotonin and acetylcholine signalling.

Specifications

Molecular weight 887.0 Da
Sequence Met-Glu-His-Phe-Pro-Gly-Pro
Purity ≥98% (HPLC)
Form Lyophilised powder
Storage −20°C
Origin UK
Research use only. Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.
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