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GHK-Cu

GHK-Cu

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Copper-binding tripeptide reported to influence the expression of ~4,000 human genes.

Overview

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide found in human plasma, where concentrations decline with age. It is one of the most heavily studied peptides in regenerative and cosmetic research.

Research applications

  • Collagen and elastin synthesis pathways
  • Wound healing and tissue remodelling
  • Antioxidant defence systems
  • Inflammatory cytokine suppression
  • Angiogenesis
  • Gene expression associated with ageing

Mechanism of action

The histidine residue binds a copper ion, and the resulting complex carries copper into the cell. Gene expression studies report influence over roughly 4,000 human genes — upregulating tissue-remodelling pathways and growth factors including TGF-β and VEGF while suppressing inflammatory signalling.

Specifications

Molecular weight 340.4 Da
Sequence Gly-His-Lys
Purity ≥98% (HPLC)
Form Lyophilised powder
Storage −20°C
Origin UK
Research use only. Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.
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