{"product_id":"semax","title":"Semax","description":"\u003cp\u003eSynthetic ACTH(4-10) analogue developed for neurological research.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eSemax is a synthetic heptapeptide analogue of ACTH(4-10), developed at a Moscow research institute in the 1980s for stroke and cognitive impairment research. The hormonal activity of the parent fragment is engineered out and a Pro-Gly-Pro tail added to resist degradation.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eBDNF upregulation\u003c\/li\u003e\n\u003cli\u003eMemory consolidation in research models\u003c\/li\u003e\n\u003cli\u003eNeuroprotection following ischaemic events\u003c\/li\u003e\n\u003cli\u003eDopaminergic and serotonergic modulation\u003c\/li\u003e\n\u003cli\u003eNeuronal growth and synaptic plasticity\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eActs on melanocortin receptors and markedly upregulates brain-derived neurotrophic factor, the protein governing neuron growth, maintenance and synaptic plasticity. It also modulates the enkephalin system and influences dopamine, serotonin and acetylcholine signalling.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e887.0 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSequence\u003c\/td\u003e\n\u003ctd\u003eMet-Glu-His-Phe-Pro-Gly-Pro\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"10mg","offer_id":65659077820765,"sku":"PPUK-SEMAX-1","price":31.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069","url":"https:\/\/powerpeptidesuk.com\/products\/semax","provider":"PowerPeps","version":"1.0","type":"link"}