{"product_id":"mots-c","title":"MOTS-C","description":"\u003cp\u003eOne of the few known peptides encoded by mitochondrial rather than nuclear DNA.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eMOTS-C is a mitochondria-derived peptide encoded by the mitochondrial genome — one of only a handful known to science. It functions as a metabolic regulator, with research covering insulin sensitivity, adiposity and exercise response.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eInsulin sensitivity in research models\u003c\/li\u003e\n\u003cli\u003eAMPK activation — the cellular energy sensor\u003c\/li\u003e\n\u003cli\u003eDiet-induced obesity markers\u003c\/li\u003e\n\u003cli\u003ePhysical endurance and muscle response\u003c\/li\u003e\n\u003cli\u003eFolate cycle and de novo purine synthesis\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eUnder metabolic stress MOTS-C translocates out of the mitochondrion and into the nucleus, where it acts directly on gene expression. It activates AMPK and inhibits the folate-methionine cycle, redirecting metabolism toward fat oxidation.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e2,174.5 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"20mg","offer_id":65659077525853,"sku":"PPUK-MOTSC-1","price":50.0,"currency_code":"GBP","in_stock":true},{"title":"40mg","offer_id":65659171078493,"sku":"PPUK-MOTSC-2","price":90.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069","url":"https:\/\/powerpeptidesuk.com\/products\/mots-c","provider":"PowerPeps","version":"1.0","type":"link"}