{"title":"Skin \u0026 Aesthetics","description":"\u003cp\u003eCompounds studied in dermal, collagen and pigmentation research. Laboratory research use only.\u003c\/p\u003e","products":[{"product_id":"ghk-cu","title":"GHK-Cu","description":"\u003cp\u003eCopper-binding tripeptide reported to influence the expression of ~4,000 human genes.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eGHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide found in human plasma, where concentrations decline with age. It is one of the most heavily studied peptides in regenerative and cosmetic research.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eCollagen and elastin synthesis pathways\u003c\/li\u003e\n\u003cli\u003eWound healing and tissue remodelling\u003c\/li\u003e\n\u003cli\u003eAntioxidant defence systems\u003c\/li\u003e\n\u003cli\u003eInflammatory cytokine suppression\u003c\/li\u003e\n\u003cli\u003eAngiogenesis\u003c\/li\u003e\n\u003cli\u003eGene expression associated with ageing\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eThe histidine residue binds a copper ion, and the resulting complex carries copper into the cell. Gene expression studies report influence over roughly 4,000 human genes — upregulating tissue-remodelling pathways and growth factors including TGF-β and VEGF while suppressing inflammatory signalling.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e340.4 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSequence\u003c\/td\u003e\n\u003ctd\u003eGly-His-Lys\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"50mg","offer_id":65659076280669,"sku":"PPUK-GHKCU-1","price":25.0,"currency_code":"GBP","in_stock":true},{"title":"100mg","offer_id":65659076313437,"sku":"PPUK-GHKCU-2","price":45.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"},{"product_id":"ahk-cu","title":"AHK-Cu","description":"\u003cp\u003eCopper-binding tripeptide studied in follicular and dermal research.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eAHK-Cu (alanyl-histidyl-lysine copper) is a copper-binding tripeptide closely related to GHK-Cu, studied primarily in hair follicle and dermal papilla research rather than general dermal remodelling.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eDermal papilla cell proliferation in research models\u003c\/li\u003e\n\u003cli\u003eFollicular growth phase signalling\u003c\/li\u003e\n\u003cli\u003eVEGF expression and local microcirculation\u003c\/li\u003e\n\u003cli\u003eCollagen synthesis pathways\u003c\/li\u003e\n\u003cli\u003eCopper delivery to the cell\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eBinds a copper ion through its histidine residue and carries it into the cell. Research reports upregulation of VEGF and stimulation of dermal papilla cells, the population governing follicular cycling.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e~340 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSequence\u003c\/td\u003e\n\u003ctd\u003eAla-His-Lys\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"100mg","offer_id":65659180777821,"sku":"PPUK-AHKCU-1","price":48.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"}],"url":"https:\/\/powerpeptidesuk.com\/collections\/skin-aesthetics.oembed","provider":"PowerPeps","version":"1.0","type":"link"}