{"title":"Longevity \u0026 Energy","description":"\u003cp\u003eCompounds studied in mitochondrial function, AMPK and sirtuin pathway research.\u003c\/p\u003e","products":[{"product_id":"nad-plus","title":"NAD+","description":"\u003cp\u003eCoenzyme required for over 500 enzymatic reactions, including ATP production.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eNicotinamide adenine dinucleotide is an essential coenzyme present in every living cell, central to energy metabolism, DNA repair and cellular signalling. Cellular concentrations decline with age, which is why it recurs throughout longevity research.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eElectron transport chain and ATP production\u003c\/li\u003e\n\u003cli\u003eSirtuin (SIRT1–7) activation\u003c\/li\u003e\n\u003cli\u003ePARP-mediated DNA repair\u003c\/li\u003e\n\u003cli\u003eNeuroprotection research\u003c\/li\u003e\n\u003cli\u003eMetabolic regulation and insulin sensitivity\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eActs as an electron carrier in the mitochondrial electron transport chain, the process that ultimately yields ATP. It is also the required substrate for PARP enzymes, which repair DNA damage, and sirtuins, which regulate inflammation, metabolism and cellular ageing pathways.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e663.4 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eSterile or bacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"500mg","offer_id":65659077263709,"sku":"PPUK-NADPLUS-1","price":55.0,"currency_code":"GBP","in_stock":true},{"title":"1000mg","offer_id":65659077296477,"sku":"PPUK-NADPLUS-2","price":80.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"},{"product_id":"mots-c","title":"MOTS-C","description":"\u003cp\u003eOne of the few known peptides encoded by mitochondrial rather than nuclear DNA.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eMOTS-C is a mitochondria-derived peptide encoded by the mitochondrial genome — one of only a handful known to science. It functions as a metabolic regulator, with research covering insulin sensitivity, adiposity and exercise response.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eInsulin sensitivity in research models\u003c\/li\u003e\n\u003cli\u003eAMPK activation — the cellular energy sensor\u003c\/li\u003e\n\u003cli\u003eDiet-induced obesity markers\u003c\/li\u003e\n\u003cli\u003ePhysical endurance and muscle response\u003c\/li\u003e\n\u003cli\u003eFolate cycle and de novo purine synthesis\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eUnder metabolic stress MOTS-C translocates out of the mitochondrion and into the nucleus, where it acts directly on gene expression. It activates AMPK and inhibits the folate-methionine cycle, redirecting metabolism toward fat oxidation.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e2,174.5 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"20mg","offer_id":65659077525853,"sku":"PPUK-MOTSC-1","price":50.0,"currency_code":"GBP","in_stock":true},{"title":"40mg","offer_id":65659171078493,"sku":"PPUK-MOTSC-2","price":90.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"},{"product_id":"epithalon","title":"Epithalon","description":"\u003cp\u003eSynthetic pineal tetrapeptide central to telomerase research.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eEpithalon (also written Epitalon) is a synthetic tetrapeptide derived from Epithalamin, a pineal gland extract characterised by Vladimir Khavinson. It is among the most cited compounds in telomere and pineal ageing research.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eTelomerase activity in cell culture\u003c\/li\u003e\n\u003cli\u003eTelomere length in fibroblast models\u003c\/li\u003e\n\u003cli\u003ePineal function and melatonin rhythm restoration\u003c\/li\u003e\n\u003cli\u003eAntioxidant and lipid peroxidation markers\u003c\/li\u003e\n\u003cli\u003eLifespan studies in animal models\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eReported to induce expression of the telomerase catalytic subunit (hTERT), permitting continued telomere elongation in dividing cells. Research also describes normalisation of pineal melatonin secretion and cortisol rhythm in aged models.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e390.3 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSequence\u003c\/td\u003e\n\u003ctd\u003eAla-Glu-Asp-Gly\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"50mg","offer_id":65659184775517,"sku":"PPUK-EPITHALON-1","price":95.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"}],"url":"https:\/\/powerpeptidesuk.com\/collections\/longevity-energy.oembed","provider":"PowerPeps","version":"1.0","type":"link"}