{"title":"Hormone \u0026 Endocrine","description":"\u003cp\u003eReference compounds for endocrine and receptor-agonism research. Laboratory research use only.\u003c\/p\u003e","products":[{"product_id":"kisspeptin","title":"Kisspeptin-10","description":"\u003cp\u003eHypothalamic neuropeptide sitting at the top of the reproductive signalling cascade.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eKisspeptin, encoded by the KISS1 gene, acts as the master regulator of the hypothalamic-pituitary-gonadal axis. Research investigates its role in GnRH pulse generation and reproductive endocrinology.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eGnRH pulse generation\u003c\/li\u003e\n\u003cli\u003eLH and testosterone response in male research models\u003c\/li\u003e\n\u003cli\u003eFertility research in hypogonadal models\u003c\/li\u003e\n\u003cli\u003ePCOS and hypothalamic amenorrhoea research\u003c\/li\u003e\n\u003cli\u003eActs upstream — no direct steroid activity\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eBinds GPR54 (KISS1R) receptors on GnRH neurons in the hypothalamus, triggering pulsatile GnRH release. That cascade drives LH and FSH secretion from the pituitary, which in turn drives gonadal hormone production.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e1,302.5 Da (Kisspeptin-10)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"10mg","offer_id":65659083456861,"sku":"PPUK-KISSPEPTIN-1","price":42.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"},{"product_id":"hcg","title":"HCG","description":"\u003cp\u003eGlycoprotein hormone that mimics LH at gonadal receptors.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eHuman chorionic gonadotropin is a glycoprotein hormone that acts on the same receptor as luteinising hormone. It is extensively studied in endocrine research, fertility science and hormonal recovery models.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eLH-mimetic action at Leydig cell receptors\u003c\/li\u003e\n\u003cli\u003eGonadal function maintenance in research models\u003c\/li\u003e\n\u003cli\u003eSpermatogenesis research\u003c\/li\u003e\n\u003cli\u003eOvulation induction research\u003c\/li\u003e\n\u003cli\u003eTesticular atrophy prevention in hormone research\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eBinds LH\/hCG receptors (LHCGR) on Leydig cells, triggering intracellular cAMP production and stimulating testosterone synthesis — effectively substituting for the pituitary LH signal without altering HPG axis feedback in the same way.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e~36,700 Da (glycoprotein)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C; 2–8°C reconstituted\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"500 IU","offer_id":65659173405021,"sku":"PPUK-HCG-1","price":25.0,"currency_code":"GBP","in_stock":true},{"title":"1000 IU","offer_id":65659173437789,"sku":"PPUK-HCG-2","price":45.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"},{"product_id":"melatonin-1","title":"Melatonin 1","description":"\u003cp\u003ePineal indoleamine hormone and principal circadian timing signal.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eMelatonin is the indoleamine hormone secreted by the pineal gland in response to darkness, acting as the body's principal circadian timing signal.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eCircadian rhythm entrainment in research models\u003c\/li\u003e\n\u003cli\u003eMT1 and MT2 receptor binding studies\u003c\/li\u003e\n\u003cli\u003eFree-radical scavenging and antioxidant assays\u003c\/li\u003e\n\u003cli\u003eMitochondrial protection research\u003c\/li\u003e\n\u003cli\u003eSeasonal and photoperiod signalling\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eBinds MT1 and MT2 G-protein coupled receptors, suppressing neuronal firing in the suprachiasmatic nucleus and shifting circadian phase. It also acts directly as a free-radical scavenger independent of receptor binding.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e232.3 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C, protect from light\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"10mg","offer_id":65659180843357,"sku":"PPUK-MELATONIN1-1","price":38.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"},{"product_id":"melatonin-2","title":"Melatonin 2","description":"\u003cp\u003ePineal indoleamine hormone - second production line.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eA second melatonin presentation held as a separate line. Same active compound and specification; kept distinct for batch and supply tracking.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eCircadian rhythm entrainment in research models\u003c\/li\u003e\n\u003cli\u003eMT1 and MT2 receptor binding studies\u003c\/li\u003e\n\u003cli\u003eFree-radical scavenging and antioxidant assays\u003c\/li\u003e\n\u003cli\u003eComparative batch and supply studies\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eBinds MT1 and MT2 G-protein coupled receptors, suppressing neuronal firing in the suprachiasmatic nucleus and shifting circadian phase. It also acts directly as a free-radical scavenger independent of receptor binding.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e232.3 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C, protect from light\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"10mg","offer_id":65659180908893,"sku":"PPUK-MELATONIN2-1","price":38.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"},{"product_id":"tesamorelin","title":"Tesamorelin","description":"\u003cp\u003eStabilised GHRH analogue studied in visceral adipose research.\u003c\/p\u003e\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eTesamorelin is a stabilised synthetic analogue of growth hormone-releasing hormone (GHRH), modified with a trans-3-hexenoyl group at the N-terminus to resist enzymatic degradation.\u003c\/p\u003e\u003ch3\u003eResearch applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eGHRH receptor agonism at the pituitary\u003c\/li\u003e\n\u003cli\u003eEndogenous, pulsatile GH release\u003c\/li\u003e\n\u003cli\u003eVisceral adipose tissue in research models\u003c\/li\u003e\n\u003cli\u003eIGF-1 response studies\u003c\/li\u003e\n\u003cli\u003eLipid profile and triglyceride markers\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eMechanism of action\u003c\/h3\u003e\u003cp\u003eBinds GHRH receptors on pituitary somatotrophs, stimulating the release of the body's own growth hormone in a pulsatile pattern rather than supplying exogenous GH. The N-terminal modification markedly extends half-life against DPP-4 cleavage.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e5,135.9 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥98% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStorage\u003c\/td\u003e\n\u003ctd\u003e−20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eUK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003cdiv class=\"sn-note\"\u003e\n\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Supplied strictly for in-vitro laboratory research. Not for human or animal consumption, and not for diagnostic or therapeutic use. To be handled only by qualified professionals. You must be 18 or over to purchase. Certificate of analysis available for every batch on request.\u003c\/div\u003e","brand":"Power Peptide UK","offers":[{"title":"10mg","offer_id":65659184906589,"sku":"PPUK-TESAMORELIN-1","price":110.0,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":65659184939357,"sku":"PPUK-TESAMORELIN-2","price":185.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1102\/9459\/7981\/files\/power-peptide-uk-vial.jpg?v=1787419069"}],"url":"https:\/\/powerpeptidesuk.com\/collections\/hormone-endocrine.oembed","provider":"PowerPeps","version":"1.0","type":"link"}